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High efficiency particulate air (HEPA) filters are 99.97 percent efficient against particles which are at 0.3 microns (about 300x smaller than the diameter of human hair) or larger. These pleated cartridges feature a large surface area in a very small diameter, low-profile cartridge. Used in applications such as soldering with lead, working near asbestos or tile or brick cutting. Approved by NIOSH under the NIOSH 42 CFR 84 respirator certification regulations; approved for the P100 filter classification. SWX00319 Replacement Cartridge.